On March 12, the Central Epidemic Command Center (CECC) announced the 49th confirmed case of coronavirus disease 2019 (COVID-19) in Taiwan. Case #49 is an over-40-year-old female who resides in northern Taiwan. She transited through the United Kingdom for Ireland from Taiwan on February 21. She traveled to Belgium from Ireland on March 4. She transited in Turkey from Belgium on March 7 and returned to Taiwan on March 8. Case #49 didn’t have any symptom when entering Taiwan but she developed a headache, tiredness and a sore throat after returning home. She sought medical care at a hospital and was reported and tested for COVID-19 on March 10. Infection with COVID-19 was laboratory-confirmed in the case on March 12. Case #49 is being treated in a negative pressure isolation ward.